论文标题
Shot-Noise Limited，基于超大型的光学相干断层扫描
Shot-noise limited, supercontinuum based optical coherence tomography
论文作者
论文摘要
我们提出了第一次演示shot-noise Limited超脑谱域光学域光学连贯层造影术（SD-OCT），轴向分辨率为5.9 $μ$ m，在1370 nm的中心波长下。当前基于超副局的SD-OCT系统无法在Shot-Noise Limited检测方案中操作，因为超脑源的严重脉搏到脉冲相对强度噪声。为了克服这一缺点，我们基于由飞秒激光泵送的全正常分散（ANDI）纤维开发了低噪声超脑源。将我们90 MHz Andi SuperContinuum源的噪声性能与以80和320 MHz重复率运行的两个商业来源的噪声性能。我们表明，在较高的对比度，更好的灵敏度和改善的穿透力方面，Andi SuperContinuum源的低噪声可显着改善OCT图像。从皮肤，视网膜和多层堆栈的SD-OCT成像中，我们得出的结论是，基于SuperContinuum的SD-OCT可以进入Shot-Noise Limited检测的领域。
We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with axial resolution of 5.9 $μ$m at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT systems cannot be operated in the shot-noise limited detection regime because of severe pulse-to-pulse relative intensity noise of the supercontinuum source. To overcome this disadvantage we have developed a low-noise supercontinuum source based on an all-normal dispersion (ANDi) fiber, pumped by a femtosecond laser. The noise performance of our 90 MHz ANDi supercontinuum source is compared to that of two commercial sources operating at 80 and 320 MHz repetition rate. We show that the low noise of the ANDi supercontinuum source improves the OCT images significantly in terms of both higher contrast, better sensitivity, and improved penetration. From SD-OCT imaging of skin, retina, and multi-layer stacks we conclude that supercontinuum-based SD-OCT can enter the domain of shot-noise limited detection.
