论文标题

用基于多模纤维的全息内窥镜观察远处的物体

Observing distant objects with a multimode fibre-based holographic endoscope

论文作者

Leite, Ivo T., Turtaev, Sergey, Flaes, Dirk E. Boonzajer, Čižmár, Tomáš

论文摘要

全息波前的操纵可以使头发 - 纯净的多模光纤转换为微创无透镜成像仪器,传达的信息密度比传统的内窥镜传达得更高。他们最突出的应用集中在访问精致的环境(包括深脑室)以及记录与仪器远端近端结构的微米尺度分辨率图像。在这里,我们介绍了一种替代的“ Farfield”内窥镜,能够在较大的景深中对宏观对象进行成像。尺寸为0.2 $ \ times $ 0.4毫米$^2 $的内窥镜轴由两个平行的光纤组成,一个用于照明,第二个用于信号收集。考虑到通过Step-Index多模纤维的光传输的特定特征,该系统针对速度,功率效率和信号质量进行了优化。成像质量的特征在20至400毫米之间的距离进行了研究。作为概念验证,我们提供了通常用作生物医学相关条件的幻影的甜辣椒腔内成像。此外,我们在功能机械时钟上测试性能,从而在动态变化的环境中验证其适用性。随着性能达到视频内窥镜的标准定义,这项工作为在临床和诊断应用中剥削微不足道的全息镜的开发铺平了道路。

Holographic wavefront manipulation enables converting hair-thin multimode optical fibres into minimally invasive lensless imaging instruments conveying much higher information densities than conventional endoscopes. Their most prominent applications focus on accessing delicate environments, including deep brain compartments, and recording micrometre-scale resolution images of structures in close proximity to the distal end of the instrument. Here, we introduce an alternative 'farfield' endoscope, capable of imaging macroscopic objects across a large depth of field. The endoscope shaft with dimensions of 0.2$\times$0.4 mm$^2$ consists of two parallel optical fibres, one for illumination and the second for signal collection. The system is optimized for speed, power efficiency and signal quality, taking into account specific features of light transport through step-index multimode fibres. The characteristics of imaging quality are studied at distances between 20 and 400 mm. As a proof-of-concept, we provide imaging inside the cavities of a sweet pepper commonly used as a phantom for biomedically relevant conditions. Further, we test the performance on a functioning mechanical clock, thus verifying its applicability in dynamically changing environments. With performance reaching the standard definition of video endoscopes, this work paves the way towards the exploitation of minimally-invasive holographic micro-endoscopes in clinical and diagnostics applications.

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