论文标题
树突运输：突触缩放和结构可塑性
Dendritic trafficking: synaptic scaling and structural plasticity
论文作者
论文摘要
神经元电路内部通过许多稳态机制调节电信号传导。据信，两种突出的机制，即突触缩放和结构可塑性，可以通过使用负反馈来修改网络连接的强度和空间范围来维持平均活性。但是，这两种机制都在相对较慢的时间尺度上运行，因此由于延迟而面临基本限制。我们表明，这些机制在保持大型网络中的稳定性方面扮演着互补的作用。特别是，即使是相对较慢的增长动态也可以显着提高超出突触缩放的性能。
Neuronal circuits internally regulate electrical signaling via a host of homeostatic mechanisms. Two prominent mechanisms, synaptic scaling and structural plasticity, are believed to maintain average activity within an operating range by modifying the strength and spatial extent of network connectivity using negative feedback. However, both mechanisms operate on relatively slow timescales and thus face fundamental limits due to delays. We show that these mechanisms fulfill complementary roles in maintaining stability in a large network. In particular, even relatively, slow growth dynamics improves performance significantly beyond synaptic scaling alone.
