论文标题
跨颗粒阶段显微镜（CGM）：内部实验（Insilex）算法，噪声和准确性
Cross-grating phase microscopy (CGM): In-silico experiment (insilex) algorithm, noise and accuracy
论文作者
论文摘要
跨颗粒相显微镜（CGM）是一种基于二维衍射光栅（交叉晶格）和常规摄像机传感器的关联，是一种定量相显微镜技术，并以毫米的距离隔开。这种简单的关联使单个图像采集的光束（强度和相位）的复杂电场振幅进行了高分辨率成像。虽然CGM已用于在过去十年中用于细胞生物学和纳米光学方面的计量应用，但关于其基本知识的研究很少，尤其是对于显微镜社区。在本文中，我们提供了一种数值算法，该算法能够使用计算机均值轻松改变并观察所有CGM实验参数的效果。在本文的框架中，我们通过使用它来解释和量化几个重要CGM参数（光栅相机距离，像素尺寸，光强度，数值孔等）的影响来说明该数值算法的兴趣。这项工作的目的是将CGM的限制推向生物显微镜和纳米光子学中的高级应用。
Cross-grating phase microscopy (CGM) is a quantitative phase microscopy technique based on the association of a 2-dimensional diffraction grating (cross-grating) and a regular camera sensor, separated by a millimetric distance. This simple association enables the high-resolution imaging of the complex electric field amplitude of a light beam (intensity and phase) from a single image acquisition. While CGM has been used for metrology applications in cell biology and nanophotonics this last decade, there has been few studies on its basics, especially for the microscopy community. In this article, we provide a numerical algorithm that enables the in silico (i.e. computer-simulated) data acquisition, to easily vary and observe the effects of all the CGM experimental parameters using computer means. In the frame on this article, we illustrate the interest of this numerical algorithm by using it to explain and quantify the effects of several important CGM parameters (grating-camera distance, pixel size, light intensity, numerical apertures, etc) on the noise, precision and trueness of CGM measurements. This work is aimed to push the limits of CGM toward advanced applications in biomicroscopy and nanophotonics.
