论文标题
通过多体柔性孔的终端聚合物易位
End-pulled polymer translocation through a many-body flexible pore
论文作者
论文摘要
本文研究了均聚物通过柔性孔转移的特征。该通道被建模为由具有两个弹性参数的单体组成的单层管：弹簧样的两个身体相互作用和弯曲三个身体召回相互作用。为了确保系统的稳定性，膜是由具有疏水体（内部）的脂质双层结构（内部）的，而孔在两个边缘的亲水性。聚合物通过悬臂从顺式侧向跨侧端部，通过弹簧连接到悬臂，能够在易位过程中测量作用在聚合物上的力。所有结构都对聚合物的单体的影响反应，其组成体的运动产生。在这些条件下，悬臂完成的工作显示出具有弹性常数的非单调行为，揭示了参数区域中类似谐振的行为。此外，注册为时间函数的力光谱能够记录孔内聚合物进程的主要动力学。
This paper studies the features of a homopolymer translocating through a flexible pore. The channel is modeled as a monolayer tube composed by monomers with two elastic parameters: spring-like two body interaction and bending three body recall interaction. In order to guarantee the stability of the system, the membrane is compounded by a lipid bilayer structure having hydrophobic body (internal), while the pore is hydrophilic in both edges. The polymer is end-pulled from the cis-side to the trans-side by a cantilever, to which is connected through a spring able to measure the force acting on the polymer during the translocation. All the structure reacts to the impacts of the monomers of the polymer with vibrations generated by the movement of its constituent bodies. In these conditions, the work done by the cantilever shows a nonmonotonic behavior with the elastic constant, revealing a resonant-like behavior in a parameter region. Moreover, the force spectroscopy registered as a function of time, is able to record the main kinetics of the polymer progression inside the pore.
