论文标题
小型动物生物磁场的应用
Small animal biomagnetism applications
论文作者
论文摘要
人脑,神经系统和心脏的功能是基于电信号的传导。这些电信号还会产生磁场,这些磁场延伸到人体之外。放置在人体外部的高度敏感的磁力计,例如超导量子干扰装置磁力计或光泵送的磁力计,可以检测到这些生物磁场,并提供非侵入性测量值。大脑活动,神经冲动和心脏活动。动物模型在医学研究中广泛使用,包括疾病诊断和药物测试。我们使用光学泵送磁力仪回顾了动物模型上的生物磁记录的话题,并介绍了有关检测青蛙坐骨神经中神经冲动的实验,并在孤立的豚鼠心脏中进行了心脏跳动。
The functioning of the human brain, nervous system and heart is based on the conduction of electrical signals. These electrical signals also create magnetic fields which extend outside the human body. Highly sensitive magnetometers, such as superconducting quantum interference device magnetometers or optically pumped magnetometers, placed outside the human body can detect these biomagnetic fields and provide non-invasive measurements of e.g. brain activity, nerve impulses, and cardiac activity. Animal models are used widely in medical research, including for disease diagnostics and for drugs testing. We review the topic of biomagnetic recordings on animal models using optically pumped magnetometers, and present our experiments on detecting nerve impulses in the frog sciatic nerve and the heart beat in an isolated guinea pig heart.