论文标题
不确定性估计的经颅超声模拟
Transcranial ultrasound simulation with uncertainty estimation
论文作者
论文摘要
经颅超声模拟越来越多地用于预测大脑超声疗法的原位暴露参数。但是，从计算机断层扫描（CT）图像中估计头骨和大脑的声学培养基特性可能存在很大的不确定性。在这里，我们展示了如何使用线性不确定性传播以计算有效的方式预测模拟声场中所产生的不确定性。在500 kHz处使用聚焦碗换能器的代表性经颅模拟的结果表明，使用Monte Carlo获得的无偏见不确定性估计。
Transcranial ultrasound simulations are increasingly used to predict in situ exposure parameters for ultrasound therapies in the brain. However, there can be considerable uncertainty in estimating the acoustic medium properties of the skull and brain from computed tomography (CT) images. Here, we show how the resulting uncertainty in the simulated acoustic field can be predicted in a computationally efficient way using linear uncertainty propagation. Results for a representative transcranial simulation using a focused bowl transducer at 500 kHz show good agreement with unbiased uncertainty estimates obtained using Monte Carlo.
